Alignment of SARS-Cov-2 Spike Protein Compared with Ebola, and Herpes Simplex Viruses in Human Murine and Bats Volume 2 - Issue 3

Hend M Tag^1,2*, Salwa S Bawazir¹ and Ibtihal H Badawi¹

• ¹Department of Biology, College of Science and Arts at Khulais, University of Jeddah, Saudi Arabia
• ²Department of Zoology, Faculty of Sciences, Suez Canal University, Egypt

Received: February 08, 2021   Published: February 18, 2021

Corresponding author: Hend MT, Department of Biology and zoology, College of Science and Arts at Khulais, University of Jeddah, Jeddah, Saudi Arabia

DOI: 10.32474/LOJPCR.2021.02.000140

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Abstract

Our analytical approach consisted in sequence alignment analysis of spike protein in different viruses, followed by construction of phylogenetic tree. Additionally, we investigated some commotional parameters on the protein sequence determining chemical composition as well as estimated PI .Our observation revealed significant difference in S protein between the 3 tested viruses in different species These differences may have significant implications on pathogenesis and entry to host cell.

Abstract| Introduction| Materials and Methods| Results| Discussion| Conclusion| Conflicts of Interest| References|