Systemic Fungal infection of skin is also known as mycosis. Mycosis is a common fungal infection affecting human skin and
causes different dermatophyte infections. Fungal infections is panic rate which presenting number of challenge to healthcare
professionals. This rising rate is directly related to the growing population of immune compromised individuals thus results from
changes in medical practice like use of immunosuppressive drugs and rigorous chemotherapy. Now there are modern aggressive
treatment was used to control fungal infection in the body. The purpose of this review is to highlight the different novel diagnostic
approaches for treatments for fungal infections.
Keywords: Fungal infection; types; characteristics; conventional; novel drug formulation
Fungal infection (fungus) is that kind of infection which is
a germ or microbe that causes infections to mammals. Another
words fungus referred as mycology and in plural it is called as fungi.
Fungus has become rise throughout the past decade. The fraction of
weak patients is rising, paralleling the surplus use of immunological
disorder therapies. The circumstances incline the patients to
fungal infection have hematopoietic stem cell, transplantation and
therapy as well as preterm birth etc. Among the varied opportunist
pathogens, fungi express a significant and necessary threat. Fungal
microbes are overabundant in nature (Table 1). They are frequent
colonizers on varied human tissue layer surfaces, wherever they
will live by evading host defenses (Table2).
Table 1: Types of Fungal Infection.
Table 2: Conventional and Novel Delivery Systems for treating fungal infections.
Characteristics of fungi [1]
.
a. Parasite
b. Identify by reproduction
c. Branched Filaments
Major Antifungal Agents
.
a. Fluoropyrimidines
b. Polyenes
c. Azoles
d. Echinocandins
e. Polyenes
The best way to deal with the ideal management of fungal
infection is firstly finding and identify the causative agents and
suitable treatment could be began as soon as possible (Table 3).
But these days novel treatments are used for the superficial fungal
infection. Which reduced the toxicity and increase the efficacy
of these drugs. They are more capable of release the drug in
sustained or controlled or minimizing the adverse effect of drugs
such as allergic reaction and itching [1-28]. Thus, novel drug
delivery system would be considered as highly efficient and better
alternative for infection.
Table 3: Novel drug formulation used of Fungal Infection.
Strober BE, Washenik K, Shupak JL (2003) Principles of topical therapy. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, (eds.). Fitzpatrick’s dermatology in general medicine, New York, NY: McGrawHill, USA 2: 2319-2323.
Poornima G, Rani KS, Brahmaiah B, Padmaja K, Pratyusha Ch (2013) Nail Drug Delivery System-A Novel Approaches for Drug Delivery System. International Journal of Advanced Pharmaceutics 3(2): 102-109.