Nanotechnology is undergoing a vast expansion in materials science, Research and Development. Nano scientists are focusing
on synthesis and development of nanoparticles, nanomaterials, and bio nano composite materials. The drug delivery is also a recent
development where in bio nano materials are being used for diagnosis of the various diseases. The synthesis of nanomaterials at
large scale causes health risk due to the exposure via inhalation, skin contacts and ingestion; based on the characterisation of bio
nano materials. The use of bio nanomaterials in drug delivery as well as the environment exposure during the large-scale synthesis
of nanomaterials, the bio nanomaterials into human body.The exact mechanisms, chemical reactivity and enzymatic reaction is not
well understood, documented, and studied. Therefore, the intake bio nanomaterials via drug delivery or environment exposure
amounts to health risk and need to be studied in detail.