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ISSN: 2690-5787

LOJ Immunology  & Infectious Disease

Mini Review Open Access

Microbes and ReA

Volume 1 - Issue 2

Binit Vaidya* and Shweta Nakarmi

Received: August 20, 2019;   Published: August 28, 2019

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Reactive arthritis (ReA) belongs to a group of diseases under spondyloarthritis (SpA). It is a systemic disease triggered by an infection at a distant site, other than joint. The infectious triggers are mostly genitourinary, gastrointestinal or respiratory tract. An association has been established between arthritis and micro-organisms like Shigella, Yersinia, Salmonella, Campylobacter and Chlamydia [1]. The role of microbiomes in inflammatory arthritis and autoimmunity has been proposed decades ago. In genetically susceptible patients, infection activates Th17 mediated immune response which causes arthritis and systemic inflammation

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