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Advancements in Cardiology Research & Reports

Case Report(ISSN: 2770-5447)

Twine and Twine or Lose the Plug- Dislodged Left Atrial Appendage Closure Device Volume 1 - Issue 5

Atul Mathur1 and Ranjan Modi2*

  • 1Senior Consultant, Fortis Escorts Heart Institute, India
  • 2Associate Consultant, Fortis Escorts Heart Institute, India

Received: February 22, 2019;   Published: March 08, 2019

Corresponding author: Ranjan Modi, Associate Consultant, Fortis Escorts Heart Institute, India

DOI: 10.32474/ACR.2019.01.000124


Abstract PDF


Embolization is a known complication of LAA closure. It may be caused by insufficient anchoring of the device to the appendage or to the delivery system. We present a case of embolization of amplatz cardiac plug.

Keywords: Amplatzer cardiac plug; Left atrial appendage occlusion; Device embolization

Twine and Twine or Lose the Plug- Dislodged Left Atrial Appendage Closure Device

A 70-year-old hypertensive male, post CABG and post PTCA presented with permanent AF and history of cardio embolic stroke (CHA2DS2-VASc score 5) with a significant bleeding risk (HAS BLED score 4). The patient was planned for percutaneous Left Atrial Appendage occlusion (LAAO) using a 28mm Amplatzer cardiac plug (ACP). The device after being loaded on the cable, was advanced into the sheath that was placed trans-sept ally into the Left Atrial Appendage (LAA) (Figure 1). A final check before advancing the device into LAA was a mandatory tug to the cable to ensure that the plug was securely connected to it. During this tug the ACP device was found disconnected from the cable shaft (Figure 2). At this moment we were left with two options: first was to entirely withdraw the sheath along with the dislodged plug followed by a fresh vascular access as well as a repeat puncture of the atrial septum; or the second option was to snare the plug out while retaining the transseptal position of the sheath. We chose the second option and using a snare (Figure 3) we retrieved the device by holding its proximal hub, and once out we were able to reload it securely on the cable shaft for reuse. Device embolization is a well-known complication of LAA closure with an average reported rate of less than 4% [1,2] mainly caused by insufficient anchoring. Most of them could be retrieved by snares looping techniques [3]. Embolization of the device can also happen if it is inadequately mounted on the cable shaft. A final mandatory tug given before advancing the plug out of the sheath prevents such eventuality.

Figure 1: The sheath placed trans-septally into the Left Atrial Appendage (LAA).


Figure 2: The ACP device found disconnected from the cable shaft.


Figure 3: Retrieval of the device by snare.


The following are the defined steps for ACP plug preparation:

a) Immerse device & hub end of loader in sterile saline to remove air.
b) Actively manipulate device in saline by hand to eliminate air bubbles on device.
c) Pull loading cable vice until lobe is fully retracted within loader, & stop before disc is recaptured
d) Insert distal end of delivery cable through haemostasis valve.
e) Connect delivery cable to exposed proximal end screw of device.
f) Grasp hub & rotate delivery cable clockwise until device is fully threaded on delivery cable.
g) Rotate delivery cable counter clockwise 1/8 of one turn to ensure that cable is not over tightened.

Numerous complications can be avoided if these steps are the done carefully and with utmost attention to every minute detail. In our case, we assume that excessive reverse rotation of the cable might be responsible for the device being loosely connected to the cable which got easily disconnected by the tug.


  1. Bajaj NS, Parashar A, Agarwal S, Sodhi N, Poddar KL, et al. (2014) Percutaneous left atrial appendage occlusion for stroke prophylaxis in nonvalvular atrial fibrillation: A systematic review and analysis of observational studies. JACC Cardiovasc Interv 7(3): 296-304.
  2. Aminian A, Lalmand J, Tzikas A, Budts W, Benit E, et al. (2015) Embolization of left atrial appendage closure devices: A systematic review of cases reported with the watchman device and the amplatzer cardiac plug. Catheter Cardiovasc Interv 86(1): 128135.
  3. Perrotta L, Bordignon S, Fürnkranz A, Chun JK, Eggebrecht H, et al. (2013) Catch me if you can: Transseptal retrieval of a dislodged left atrial appendage occluder. Circ Arrhythm Electrophysiol 6(4): e64.