Prognosis and Complications of Hyperuricemia Patients Undergoing Isolated Carotid Endarterectomy Volume 2 - Issue 5

Haydar Yasa*

• Department of Cardiovascular Surgery, Health Sciences University Evliya celebi Educatıon and Research Hospıtal, Turkey

Received: December 06, 2019;   Published: January 06, 2020

Corresponding author: Haydar Yasa, Department of Cardiovascular Surgery, Health Sciences University Evliya celebi Educatıon and Research Hospıtal, kütahya, Turkey

DOI: 10.32474/ACR.2020.02.000146

 

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Abstract

Background: Despite the association of hyperuricemia with cardiovascular risk factors, it has remained controversial as to whether uric acid is an independent predictor of cardiovascular disease, with many studies in favor and others against. The results of this study are expected to enhance our knowledge regarding the role of uric acid level on outcomes of patients with carotid artery endarterectomy and thus can be used by clinician in determining patient’s prognosis.

Methods: Patients evaluation were performed by collecting prospective data on patients undergoing CEA at our hospital from September 2012 to May 2019, primary CEA was performed on 120 consecutive patients in the same surgical groups. From this sample, patients who underwent isolated CEA were selected, and this population was then divided into those with hyperurisemia (Group I) and those without hyperurisemia (Group II).Among the clinical complications that occurred following CEA, the following variables were analyzed: mortalite, x-clamp time, perioperative ICU (intensive care unit) times, entubation time, reentubationratio, hospitalization time, rehospitalization ratio, neurological complications, infectious complications, wound infection failure occurring within 30 days after the surgery.

Results: The two groups were similar according to clinical characteristics such as age, risk factors, gender, smoking, using alcohol, BMI, previous myocardial infarction, dyslipidemia, previous cerebrovascular accident. There was longer carotid x-clamp time in group I versus group II. Twenty-seven patients in Group I and 53 patients in Group II had normal blood pressure on antihypertensive medication.In group 1, neurological complications were observed only in one patient in the form of a transient ischemic attack. Coronary artery lessions have more affected Group I than Group II and number of coronary arterydiseasehavemoreGroup I ratherthanGroup II. Aditionaly periferic artery lessions have more affected Group I than Group II and number of periferic artery disease have more Group I rather than Group II. There have wound enfections in 3 patients group I and 2 patients in Group II but there haven’t statistical diferrantation.

Conclusion: Hyperuricemia, which has effects on kidney, liver, coronary vessels, carotid and other peripheral vessels, should be considered a metabolic disease, such as a Diabetes Mellitus.

Keywords: Hyperurisemia; carotid; endarterectomy; prognosis; complication

Summary| Introduction| Patients and Methods| Surgical Technique| Follow-up| Clinical and Uric Acid Data Collection| Statistical Analysis| Results| Discussion| References|